The PTPRE Antibody (N-term) from MyBioSource.com is a Rabbit Polyclonal antibody to PTPRE. This antibody recognizes Human, and Rat antigen. The PTPRE Antibody (N-term) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is a member of the
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. Two alternatively spliced transcript
variants of this gene have been reported, one of which encodes a
receptor-type PTP that possesses a short extracellular domain, a
single transmembrane region, and two tandem intracytoplasmic
catalytic domains; Another one encodes a PTP that contains a
distinct hydrophilic N-terminus, and thus represents a
nonreceptor-type isoform of this PTP. Studies of the similar gene
in mice suggested the regulatory roles of this PTP in RAS related
signal transduction pathways, cytokines induced SATA signaling, as
well as the activation of voltage-gated K+ channels. [provided by
RefSeq]